Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27673 (2-[2-(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]car...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(CCOc2ccccc2C(N)=O)c1 Show InChI InChI=1S/C29H31N3O5/c1-21(37-24-10-3-2-4-11-24)28(34)31-15-17-32(18-16-31)29(35)23-9-7-8-22(20-23)14-19-36-26-13-6-5-12-25(26)27(30)33/h2-13,20-21H,14-19H2,1H3,(H2,30,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
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