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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27674'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM27674
PNG
(2-[2-(4-fluoro-3-{[4-(2-phenoxypropanoyl)piperazin...)
Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cc(CCOc2ccccc2C(N)=O)ccc1F
Show InChI InChI=1S/C29H30FN3O5/c1-20(38-22-7-3-2-4-8-22)28(35)32-14-16-33(17-15-32)29(36)24-19-21(11-12-25(24)30)13-18-37-26-10-6-5-9-23(26)27(31)34/h2-12,19-20H,13-18H2,1H3,(H2,31,34)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 19n/an/an/an/a7.422



KuDOS Pharmaceuticals Ltd



Assay Description
A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...

Bioorg Med Chem Lett 18: 3942-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.025
BindingDB Entry DOI: 10.7270/Q2FF3QPX
More data for this
Ligand-Target Pair