Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM318040'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM318040 (2-[4-[(4-Chloropyrimidin-2-yl)methyl]piperazin-1-y...) Show SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2nccc(Cl)n2)CC1 Show InChI InChI=1S/C17H22ClN7O/c1-23-6-2-3-12-15(23)21-17(22-16(12)26)25-9-7-24(8-10-25)11-14-19-5-4-13(18)20-14/h4-5H,2-3,6-11H2,1H3,(H,21,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.5	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...				US Patent US9624218 (2017) BindingDB Entry DOI: 10.7270/Q26112CZ
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