Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325]' and Ligand = 'BDBM231034'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] (Homo sapiens (Human))	BDBM231034 (US9340549, 51) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)[C@H]1CC[C@@H](CC1)n1c2cccc(C#N)c2[nH]c1=O |r,wU:7.8,14.15,wD:17.22,(-8.18,.02,;-6.84,.79,;-7.61,-.54,;-6.84,2.33,;-5.38,2.81,;-4.61,4.14,;-4.47,1.56,;-5.38,.32,;-4.98,-1.17,;-6.07,-2.26,;-5.67,-3.75,;-4.18,-4.14,;-3.09,-3.05,;-3.49,-1.57,;-2.93,1.56,;-2.16,2.9,;-.62,2.9,;.15,1.56,;-.62,.23,;-2.16,.23,;1.69,1.56,;2.59,.32,;2.27,-1.19,;3.42,-2.22,;4.88,-1.74,;5.2,-.24,;6.67,.24,;8.13,.72,;4.06,.79,;4.06,2.33,;2.59,2.81,;1.82,4.14,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.56	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair