Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325]' and Ligand = 'BDBM231113'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] (Homo sapiens (Human))	BDBM231113 (US9340549, 138) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)C1CC[C@@H](CC1)c1cc2ccncc2[nH]c1=O |r,wU:7.8,wD:17.22,(-7.63,-.02,;-6.29,.75,;-7.06,-.58,;-6.29,2.29,;-4.83,2.77,;-4.06,4.1,;-3.92,1.52,;-4.83,.27,;-4.43,-1.21,;-5.52,-2.3,;-5.12,-3.79,;-3.63,-4.19,;-2.54,-3.1,;-2.94,-1.61,;-2.38,1.52,;-1.61,2.85,;-.07,2.85,;.7,1.52,;-.07,.19,;-1.61,.19,;2.24,1.52,;3.01,.19,;4.55,.19,;5.32,-1.15,;6.86,-1.15,;7.63,.19,;6.86,1.52,;5.32,1.52,;4.55,2.85,;3.01,2.85,;2.24,4.19,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
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