Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM291813'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM291813 (N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...) Show SMILES Cc1cc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12)S(C)(=O)=O Show InChI InChI=1S/C22H20FN5O3S/c1-13-9-14(32(2,29)30)3-4-15(13)18-11-25-22(28-12-26-27-21(18)28)24-10-17-16-7-8-31-20(16)6-5-19(17)23/h3-6,9,11-12H,7-8,10H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JNH
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM291813 (N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...) Show SMILES Cc1cc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12)S(C)(=O)=O Show InChI InChI=1S/C22H20FN5O3S/c1-13-9-14(32(2,29)30)3-4-15(13)18-11-25-22(28-12-26-27-21(18)28)24-10-17-16-7-8-31-20(16)6-5-19(17)23/h3-6,9,11-12H,7-8,10H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JNH
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM291813 (N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...) Show SMILES Cc1cc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12)S(C)(=O)=O Show InChI InChI=1S/C22H20FN5O3S/c1-13-9-14(32(2,29)30)3-4-15(13)18-11-25-22(28-12-26-27-21(18)28)24-10-17-16-7-8-31-20(16)6-5-19(17)23/h3-6,9,11-12H,7-8,10H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...				Citation and Details BindingDB Entry DOI: 10.7270/Q29W0JNH
					More data for this Ligand-Target Pair