Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L]' and Ligand = 'BDBM173586'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM173586 ((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(4-hydroxy-3-n...) Show SMILES Oc1ccc(\C=C\C(=O)c2cc3ccccc3cc2O)cc1[N+]([O-])=O Show InChI InChI=1S/C19H13NO5/c21-17(7-5-12-6-8-18(22)16(9-12)20(24)25)15-10-13-3-1-2-4-14(13)11-19(15)23/h1-11,22-23H/b7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.19E+4	n/a	2.56E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
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