Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibition of 15-lipoxygenase soyabean | J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity of the compound against soyabean 15-lipoxygenase was evaluated | Bioorg Med Chem Lett 2: 1353-1356 (1992) Article DOI: 10.1016/S0960-894X(00)80511-9 BindingDB Entry DOI: 10.7270/Q2H41RC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tamkang University Curated by ChEMBL | Assay Description Inhibitory activity against 15-lipoxygenase was determined obtained from soya bean | Bioorg Med Chem Lett 14: 63-5 (2003) BindingDB Entry DOI: 10.7270/Q2PC31TX | |||||||||||
More data for this Ligand-Target Pair |