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Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily A member 5' and Ligand = 'BDBM50199066'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily A member 5


(Homo sapiens (Human))		BDBM50199066
PNG
(1-{[(2R)-2,3-dihydroxypropyl]oxy}-6-methoxy-4-phen...)
Show SMILES COc1ccc2c(OC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1
Show InChI InChI=1S/C20H18N2O4/c1-25-15-7-8-16-17(9-15)19(13-5-3-2-4-6-13)18(10-21)22-20(16)26-12-14(24)11-23/h2-9,14,23-24H,11-12H2,1H3/t14-/m1/s1
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n/an/a 160n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assay

J Med Chem 49: 6954-7 (2006)


Article DOI: 10.1021/jm060927v
BindingDB Entry DOI: 10.7270/Q2ST7PG7
More data for this
Ligand-Target Pair