BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50350791'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50350791 (LEVOBUPIVACAINE HYDROCHLORIDE) Show SMILES CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of wild-type human ERG channel expressed in CHO cells by whole-cell patch clamp technique				Eur J Med Chem 46: 3486-98 (2011) Article DOI: 10.1016/j.ejmech.2011.05.015 BindingDB Entry DOI: 10.7270/Q2TD9XQ6
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50350791 (LEVOBUPIVACAINE HYDROCHLORIDE) Show SMILES CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of wild-type human ERG channel expressed in HEK293 cells assessed as blockade of potassium tail current by whole-cell patch clamp techniqu...				Eur J Med Chem 46: 3486-98 (2011) Article DOI: 10.1016/j.ejmech.2011.05.015 BindingDB Entry DOI: 10.7270/Q2TD9XQ6
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair