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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily KQT member 4' and Ligand = 'BDBM50465778'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily KQT member 4


(Homo sapiens (Human))
BDBM50465778
PNG
(CHEMBL4287478)
Show SMILES C[C@H](NC(=O)[C@H]1CC(F)(F)CC[C@@H]1c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C21H23F2NO/c1-15(16-8-4-2-5-9-16)24-20(25)19-14-21(22,23)13-12-18(19)17-10-6-3-7-11-17/h2-11,15,18-19H,12-14H2,1H3,(H,24,25)/t15-,18+,19-/m0/s1
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 4.00E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activation of human Kv7.4 by patch clamp method


Bioorg Med Chem Lett 28: 3793-3797 (2018)


Article DOI: 10.1016/j.bmcl.2018.09.036
BindingDB Entry DOI: 10.7270/Q28W3H0D
More data for this
Ligand-Target Pair