Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM193042'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM193042 (US9193726, 30) Show SMILES Cc1cn(cn1)-c1ccc2C(=O)N(CC3CC(=NO3)c3cc(ccc3Cl)C(F)(F)F)CCn2c1=O |c:17| Show InChI InChI=1S/C23H19ClF3N5O3/c1-13-10-31(12-28-13)19-4-5-20-21(33)30(6-7-32(20)22(19)34)11-15-9-18(29-35-15)16-8-14(23(25,26)27)2-3-17(16)24/h2-5,8,10,12,15H,6-7,9,11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	711	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...				US Patent US9193726 (2015) BindingDB Entry DOI: 10.7270/Q22B8WT7
					More data for this Ligand-Target Pair