Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50484296'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50484296 (CHEMBL1837043) Show SMILES FC(F)(F)c1ccc(cn1)S(=O)(=O)N1C2CC(CC1c1cn[nH]c1C2)c1ccccc1 |TLB:10:13:15.17.16:24.19.23| Show InChI InChI=1S/C21H19F3N4O2S/c22-21(23,24)20-7-6-16(11-25-20)31(29,30)28-15-8-14(13-4-2-1-3-5-13)9-19(28)17-12-26-27-18(17)10-15/h1-7,11-12,14-15,19H,8-10H2,(H,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of gamma-secretase-mediated cleavage of amyloid precursor protein in human IMR32 cells after 2 hrs using MBPC-125 substrate by ELISA assay				Bioorg Med Chem Lett 21: 5791-4 (2011) Article DOI: 10.1016/j.bmcl.2011.08.008 BindingDB Entry DOI: 10.7270/Q27M0BSF
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Presenilin-1 (Homo sapiens (Human))	BDBM50484296 (CHEMBL1837043) Show SMILES FC(F)(F)c1ccc(cn1)S(=O)(=O)N1C2CC(CC1c1cn[nH]c1C2)c1ccccc1 |TLB:10:13:15.17.16:24.19.23| Show InChI InChI=1S/C21H19F3N4O2S/c22-21(23,24)20-7-6-16(11-25-20)31(29,30)28-15-8-14(13-4-2-1-3-5-13)9-19(28)17-12-26-27-18(17)10-15/h1-7,11-12,14-15,19H,8-10H2,(H,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of gamma-secretase-mediated notch cleavage in human SNC-204B8 cells after 16 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 21: 5791-4 (2011) Article DOI: 10.1016/j.bmcl.2011.08.008 BindingDB Entry DOI: 10.7270/Q27M0BSF
					More data for this Ligand-Target Pair