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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN2' and Ligand = 'BDBM118340'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))
BDBM118340
PNG
(US8653111, 83)
Show SMILES FC(F)(F)c1ccnc(c1)-n1[nH]cc(-n2ccnn2)c1=O
Show InChI InChI=1S/C11H7F3N6O/c12-11(13,14)7-1-2-15-9(5-7)20-10(21)8(6-17-20)19-4-3-16-18-19/h1-6,17H
PDB

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Similars

US Patent
n/an/a 1.90E+3n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...


US Patent US8653111 (2014)


BindingDB Entry DOI: 10.7270/Q2GH9GMD
More data for this
Ligand-Target Pair