Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50333499 ((R)-2-(8-(2-(4-fluorophenyl)-N,2-dimethylpropanami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Displacement of radioligand from human CRTH2 expressed in HEK293 cells by competitive binding assay | Bioorg Med Chem Lett 21: 841-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.084 BindingDB Entry DOI: 10.7270/Q24J0FCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50333499 ((R)-2-(8-(2-(4-fluorophenyl)-N,2-dimethylpropanami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at CRTH2 in human eosinophil assessed as effect of cellular shape change by EOS assay | Bioorg Med Chem Lett 21: 841-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.084 BindingDB Entry DOI: 10.7270/Q24J0FCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50333499 ((R)-2-(8-(2-(4-fluorophenyl)-N,2-dimethylpropanami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at human CRTH2 expressed in HEK293 cells assessed as inhibition of forskolin-induced increase intracellular [125I]cAMP level by s... | Bioorg Med Chem Lett 21: 841-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.084 BindingDB Entry DOI: 10.7270/Q24J0FCP | |||||||||||
More data for this Ligand-Target Pair |