BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50255778'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50255778 (3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 19: 778-82 (2009) Article DOI: 10.1016/j.bmcl.2008.12.027 BindingDB Entry DOI: 10.7270/Q24M94DH
deCODE Chemistry, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50255778 (3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 778-82 (2009) Article DOI: 10.1016/j.bmcl.2008.12.027 BindingDB Entry DOI: 10.7270/Q24M94DH
deCODE Chemistry, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair