Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50315528'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315528 (3-(3-methyl-1-(naphthalen-2-ylmethyl)-2-oxoindolin...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F Show InChI InChI=1S/C29H21F3N2O4S/c1-17-22-8-4-7-20(11-12-27(35)33-39(37,38)26-15-24(31)23(30)14-25(26)32)28(22)34(29(17)36)16-18-9-10-19-5-2-3-6-21(19)13-18/h2-15,17H,16H2,1H3,(H,33,35)/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315528 (3-(3-methyl-1-(naphthalen-2-ylmethyl)-2-oxoindolin...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F Show InChI InChI=1S/C29H21F3N2O4S/c1-17-22-8-4-7-20(11-12-27(35)33-39(37,38)26-15-24(31)23(30)14-25(26)32)28(22)34(29(17)36)16-18-9-10-19-5-2-3-6-21(19)13-18/h2-15,17H,16H2,1H3,(H,33,35)/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair