Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50317910'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50317910 (3-[4-[(3-Cyanophenoxy)methyl]-2-({[(1R)-1-(3,5-dim...) Show SMILES CC(C)C[C@@H](NC(=O)c1cc(COc2cccc(c2)C#N)ccc1CCC(O)=O)c1cc(C)cc(C)c1 |r| Show InChI InChI=1S/C31H34N2O4/c1-20(2)12-29(26-14-21(3)13-22(4)15-26)33-31(36)28-17-24(8-9-25(28)10-11-30(34)35)19-37-27-7-5-6-23(16-27)18-32/h5-9,13-17,20,29H,10-12,19H2,1-4H3,(H,33,36)(H,34,35)/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem 18: 3212-23 (2010) Article DOI: 10.1016/j.bmc.2010.03.028 BindingDB Entry DOI: 10.7270/Q2SF2WB7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50317910 (3-[4-[(3-Cyanophenoxy)methyl]-2-({[(1R)-1-(3,5-dim...) Show SMILES CC(C)C[C@@H](NC(=O)c1cc(COc2cccc(c2)C#N)ccc1CCC(O)=O)c1cc(C)cc(C)c1 |r| Show InChI InChI=1S/C31H34N2O4/c1-20(2)12-29(26-14-21(3)13-22(4)15-26)33-31(36)28-17-24(8-9-25(28)10-11-30(34)35)19-37-27-7-5-6-23(16-27)18-32/h5-9,13-17,20,29H,10-12,19H2,1-4H3,(H,33,36)(H,34,35)/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...				Bioorg Med Chem 18: 3212-23 (2010) Article DOI: 10.1016/j.bmc.2010.03.028 BindingDB Entry DOI: 10.7270/Q2SF2WB7
					More data for this Ligand-Target Pair