Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50293496 (2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to EP4 receptor (unknown origin) | J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Rattus norvegicus) | BDBM50293496 (2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells | Bioorg Med Chem Lett 19: 2075-8 (2009) Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 | |||||||||||
More data for this Ligand-Target Pair |