Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50079754'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079754 (CHEMBL65476 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...) Show SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(nc(N)c32)N(C)C2CC2)cc1 Show InChI InChI=1S/C24H27N5/c1-15(2)17-6-4-16(5-7-17)14-29-13-12-19-21(29)11-10-20-22(19)23(25)27-24(26-20)28(3)18-8-9-18/h4-7,10-13,15,18H,8-9,14H2,1-3H3,(H2,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health& Science University Curated by ChEMBL					Assay Description Antagonist activity at PAR1 in human platelet membranes assessed as inhibition of interaction of PAR1 with [Ala-Phe(p-F)-Arg-Cha-HArg-Tyr-NH2] by Chr...				Medchemcomm 6: 510-520 (2015) BindingDB Entry DOI: 10.7270/Q2QN68NS
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50079754 (CHEMBL65476 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...) Show SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(nc(N)c32)N(C)C2CC2)cc1 Show InChI InChI=1S/C24H27N5/c1-15(2)17-6-4-16(5-7-17)14-29-13-12-19-21(29)11-10-20-22(19)23(25)27-24(26-20)28(3)18-8-9-18/h4-7,10-13,15,18H,8-9,14H2,1-3H3,(H2,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)				Bioorg Med Chem Lett 9: 2073-8 (1999) BindingDB Entry DOI: 10.7270/Q25X284B
					More data for this Ligand-Target Pair