Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 4' and Ligand = 'BDBM286446'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 4 (Homo sapiens (Human))	BDBM286446 (6-(4-((3-Fluoro-5-(5-methoxypyridin-2-yl)benzyl)ox...) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cc(F)cc(c3)-c3ccc(OC)cn3)cc(OC)cc2o1 Show InChI InChI=1S/C27H21FN4O5S/c1-33-18-4-5-21(29-12-18)16-6-15(7-17(28)8-16)14-36-23-9-19(34-2)10-24-20(23)11-25(37-24)22-13-32-26(30-22)38-27(31-32)35-3/h4-13H,14H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite De Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US9518064 (2016) BindingDB Entry DOI: 10.7270/Q2TT4SZX
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