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Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50126486'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50126486
PNG
(CHEMBL32549 | N-(6-Amino-2-methyl-pyridin-3-ylmeth...)
Show SMILES Cc1cc2c(NCN(CC3CC3)S2(=O)=O)c(=O)n1CC(=O)NCc1ccc(N)nc1C
Show InChI InChI=1S/C20H26N6O4S/c1-12-7-16-19(23-11-25(31(16,29)30)9-14-3-4-14)20(28)26(12)10-18(27)22-8-15-5-6-17(21)24-13(15)2/h5-7,14,23H,3-4,8-11H2,1-2H3,(H2,21,24)(H,22,27)
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PubMed
 2.10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human thrombin

Bioorg Med Chem Lett 13: 1441-4 (2003)


BindingDB Entry DOI: 10.7270/Q2736Q8C
More data for this
Ligand-Target Pair