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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384011'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384011
PNG
(US10280166, Compound 279)
Show SMILES O=C(Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccsc3)c2c1)C1CC1
Show InChI InChI=1S/C26H19N7OS/c34-26(14-1-2-14)29-18-9-17(11-27-12-18)15-3-4-21-20(10-15)23(33-32-21)25-30-22-19(16-6-8-35-13-16)5-7-28-24(22)31-25/h3-14H,1-2H2,(H,29,34)(H,32,33)(H,28,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.20n/an/an/an/an/an/a



University of Nottingham



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Br J Pharmacol 144: 317-22 (2005)


BindingDB Entry DOI: 10.7270/Q22Z17VC
More data for this
Ligand-Target Pair