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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384034'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384034
PNG
(US10280166, Compound 373)
Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccc(C)s3)c2c1
Show InChI InChI=1S/C27H23N7OS/c1-14(2)27(35)30-18-10-17(12-28-13-18)16-5-6-21-20(11-16)24(34-33-21)26-31-23-19(8-9-29-25(23)32-26)22-7-4-15(3)36-22/h4-14H,1-3H3,(H,30,35)(H,33,34)(H,29,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.40n/an/an/an/an/an/a



University of Nottingham



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Br J Pharmacol 144: 317-22 (2005)


BindingDB Entry DOI: 10.7270/Q22Z17VC
More data for this
Ligand-Target Pair