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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384585'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384585
PNG
(US10285982, Compound 33)
Show SMILES Cc1ccncc1-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C25H17FN6/c1-14-6-8-27-12-20(14)21-11-19-23(13-29-21)31-32-24(19)22-10-18-17(7-9-28-25(18)30-22)15-2-4-16(26)5-3-15/h2-13H,1H3,(H,28,30)(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 642n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair