Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384680'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM384680 (US10285982, Compound 114) Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C28H24N8O/c1-16(2)9-26(37)33-19-10-18(13-30-14-19)23-12-22-25(15-32-23)35-36-27(22)24-11-21-20(5-8-31-28(21)34-24)17-3-6-29-7-4-17/h3-8,10-16H,9H2,1-2H3,(H,31,34)(H,33,37)(H,35,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Istanbul University					Assay Description Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...				Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2J105G8
					More data for this Ligand-Target Pair