Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384697'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM384697 (US10285982, Compound 262) Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2cccnc2[nH]1 Show InChI InChI=1S/C26H19N7O/c34-24(9-16-5-2-1-3-6-16)30-19-10-18(13-27-14-19)21-12-20-23(15-29-21)32-33-25(20)22-11-17-7-4-8-28-26(17)31-22/h1-8,10-15H,9H2,(H,28,31)(H,30,34)(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Istanbul University					Assay Description Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...				Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2J105G8
					More data for this Ligand-Target Pair