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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384726'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384726
PNG
(US10285983, Compound 30)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccc(F)cc3)c2c1
Show InChI InChI=1S/C29H24FN7O/c1-16(2)9-26(38)34-21-10-18(13-31-15-21)19-11-24-27(36-37-29(24)33-14-19)25-12-23-22(7-8-32-28(23)35-25)17-3-5-20(30)6-4-17/h3-8,10-16H,9H2,1-2H3,(H,32,35)(H,34,38)(H,33,36,37)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair