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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384734'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384734
PNG
(US10285983, Compound 59)
Show SMILES Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccccc3F)c2c1
Show InChI InChI=1S/C24H16FN7/c25-20-4-2-1-3-17(20)16-5-6-28-23-18(16)9-21(30-23)22-19-8-14(11-29-24(19)32-31-22)13-7-15(26)12-27-10-13/h1-12H,26H2,(H,28,30)(H,29,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair