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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384759'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384759
PNG
(US10285983, Compound 169)
Show SMILES CCC(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)N3CCCCC3)c2c1
Show InChI InChI=1S/C26H26N8O/c1-2-23(35)30-18-10-16(13-27-15-18)17-11-20-24(32-33-26(20)29-14-17)21-12-19-22(6-7-28-25(19)31-21)34-8-4-3-5-9-34/h6-7,10-15H,2-5,8-9H2,1H3,(H,28,31)(H,30,35)(H,29,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 861n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair