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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384776'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384776
PNG
(US10285983, Compound 356)
Show SMILES O=C(Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3cccs3)c2c1)C1CC1
Show InChI InChI=1S/C26H19N7OS/c34-26(14-3-4-14)30-17-8-15(11-27-13-17)16-9-20-23(32-33-25(20)29-12-16)21-10-19-18(22-2-1-7-35-22)5-6-28-24(19)31-21/h1-2,5-14H,3-4H2,(H,28,31)(H,30,34)(H,29,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 6.37E+3n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair