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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384777'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384777
PNG
(US10285983, Compound 456)
Show SMILES CN(C)CCNc1cc(F)cc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C(C)(C)C)c1
Show InChI InChI=1S/C33H34FN9O/c1-33(2,3)32(44)39-24-12-20(16-35-18-24)21-13-27-29(41-42-31(27)38-17-21)28-15-26-25(6-7-37-30(26)40-28)19-10-22(34)14-23(11-19)36-8-9-43(4)5/h6-7,10-18,36H,8-9H2,1-5H3,(H,37,40)(H,39,44)(H,38,41,42)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair