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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384787'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384787
PNG
(US10285983, Compound 781)
Show SMILES CN(C)CCNc1cc(F)cc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cnc(C)n1C
Show InChI InChI=1S/C28H28FN9/c1-16-32-15-25(38(16)4)18-11-23-26(35-36-28(23)33-14-18)24-13-22-21(5-6-31-27(22)34-24)17-9-19(29)12-20(10-17)30-7-8-37(2)3/h5-6,9-15,30H,7-8H2,1-4H3,(H,31,34)(H,33,35,36)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 4.46E+3n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair