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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM445811'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM445811
PNG
(US10669240, Compound 132)
Show SMILES CC(C)NC(=O)c1n[nH]c2ccc(cc12)-c1cncc(CN2CCC(F)(F)CC2)c1
Show InChI InChI=1S/C22H25F2N5O/c1-14(2)26-21(30)20-18-10-16(3-4-19(18)27-28-20)17-9-15(11-25-12-17)13-29-7-5-22(23,24)6-8-29/h3-4,9-12,14H,5-8,13H2,1-2H3,(H,26,30)(H,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 47n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...

US Patent US10669240 (2020)


BindingDB Entry DOI: 10.7270/Q2HQ42ZD
More data for this
Ligand-Target Pair