Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM311752'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM311752 (Ex. Cpd. 206 | US10807986, Example 206 | US1104669...) Show SMILES COCc1ccc(NC(=O)c2c(C#CCN3CCOCC3)n(c3ncnc(N)c23)C2(C)CC2)cc1F Show InChI InChI=1S/C26H29FN6O3/c1-26(7-8-26)33-20(4-3-9-32-10-12-36-13-11-32)21(22-23(28)29-16-30-24(22)33)25(34)31-18-6-5-17(15-35-2)19(27)14-18/h5-6,14,16H,7-13,15H2,1-2H3,(H,31,34)(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Regarding the conditions for measurement of in vitro inhibitory activity of compounds against RET kinase activity, the website of AnaSpec states that...				US Patent US10155768 (2018) BindingDB Entry DOI: 10.7270/Q2X350J3
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM311752 (Ex. Cpd. 206 | US10807986, Example 206 | US1104669...) Show SMILES COCc1ccc(NC(=O)c2c(C#CCN3CCOCC3)n(c3ncnc(N)c23)C2(C)CC2)cc1F Show InChI InChI=1S/C26H29FN6O3/c1-26(7-8-26)33-20(4-3-9-32-10-12-36-13-11-32)21(22-23(28)29-16-30-24(22)33)25(34)31-18-6-5-17(15-35-2)19(27)14-18/h5-6,14,16H,7-13,15H2,1-2H3,(H,31,34)(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Regarding the conditions for measurement of in vitro inhibitory activity of compounds against RET kinase activity, the website of AnaSpec states that...				Citation and Details BindingDB Entry DOI: 10.7270/Q2280BR0
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM311752 (Ex. Cpd. 206 | US10807986, Example 206 | US1104669...) Show SMILES COCc1ccc(NC(=O)c2c(C#CCN3CCOCC3)n(c3ncnc(N)c23)C2(C)CC2)cc1F Show InChI InChI=1S/C26H29FN6O3/c1-26(7-8-26)33-20(4-3-9-32-10-12-36-13-11-32)21(22-23(28)29-16-30-24(22)33)25(34)31-18-6-5-17(15-35-2)19(27)14-18/h5-6,14,16H,7-13,15H2,1-2H3,(H,31,34)(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Regarding the conditions for measurement of in vitro inhibitory activity of compounds against RET kinase activity, the website of AnaSpec states that...				US Patent US10807986 (2020) BindingDB Entry DOI: 10.7270/Q29G5QWG
					More data for this Ligand-Target Pair