Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50212747'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50212747 ((E)-1-(4-((5,6-dimethoxy-2-oxoindolin-3-ylidene)me...) Show SMILES COc1cc2NC(=O)\C(=C\c3ccc(NC(=O)Nc4ccc(O)cc4)cc3)c2cc1OC Show InChI InChI=1S/C24H21N3O5/c1-31-21-12-18-19(23(29)27-20(18)13-22(21)32-2)11-14-3-5-15(6-4-14)25-24(30)26-16-7-9-17(28)10-8-16/h3-13,28H,1-2H3,(H,27,29)(H2,25,26,30)/b19-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
National Tsing Hua University Curated by ChEMBL					Assay Description Inhibition of RET kinase				Bioorg Med Chem Lett 21: 4490-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.003 BindingDB Entry DOI: 10.7270/Q2BV7H06
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50212747 ((E)-1-(4-((5,6-dimethoxy-2-oxoindolin-3-ylidene)me...) Show SMILES COc1cc2NC(=O)\C(=C\c3ccc(NC(=O)Nc4ccc(O)cc4)cc3)c2cc1OC Show InChI InChI=1S/C24H21N3O5/c1-31-21-12-18-19(23(29)27-20(18)13-22(21)32-2)11-14-3-5-15(6-4-14)25-24(30)26-16-7-9-17(28)10-8-16/h3-13,28H,1-2H3,(H,27,29)(H2,25,26,30)/b19-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Curated by ChEMBL					Assay Description Inhibition of RET in mouse NIH3T3MEN2A cells				Bioorg Med Chem Lett 17: 3962-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.091 BindingDB Entry DOI: 10.7270/Q2HH6JSN
					More data for this Ligand-Target Pair