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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50122724'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purine nucleoside phosphorylase


(Homo sapiens (Human))
BDBM50122724
PNG
(4-Amino-5-(3,4-dihydroxy-5-hydroxymethyl-pyrrolidi...)
Show SMILES NC(=O)c1[nH]nc(C2N[C@H](CO)[C@H](O)[C@@H]2O)c1N
Show InChI InChI=1S/C9H15N5O4/c10-3-4(13-14-5(3)9(11)18)6-8(17)7(16)2(1-15)12-6/h2,6-8,12,15-17H,1,10H2,(H2,11,18)(H,13,14)/t2-,6?,7+,8-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
0.0960n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibitory activity of compound against human purine nucleoside phosphorylase(PNP)


J Med Chem 46: 155-60 (2002)


Article DOI: 10.1021/jm0203332
BindingDB Entry DOI: 10.7270/Q2DF6QJZ
More data for this
Ligand-Target Pair