Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]' and Ligand = 'BDBM16792'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM16792 (3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-chloro-1H-py...) Show SMILES N[C@H](COc1cncc(c1)-c1cc2c(Cl)n[nH]c2cn1)Cc1ccccc1 |r| Show InChI InChI=1S/C20H18ClN5O/c21-20-17-8-18(24-11-19(17)25-26-20)14-7-16(10-23-9-14)27-12-15(22)6-13-4-2-1-3-5-13/h1-5,7-11,15H,6,12,22H2,(H,25,26)/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem 15: 2441-52 (2007) Article DOI: 10.1016/j.bmc.2007.01.010 BindingDB Entry DOI: 10.7270/Q26Q1VGQ
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