Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM185587'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM185587 (US9156852, 50 | USRE47451, Example 50) Show SMILES Cc1ccc2c(Nc3ccc(OC(F)F)cc3)nccc2c1NC(=O)c1csc2c(N)ncnc12 Show InChI InChI=1S/C24H18F2N6O2S/c1-12-2-7-16-15(8-9-28-22(16)31-13-3-5-14(6-4-13)34-24(25)26)18(12)32-23(33)17-10-35-20-19(17)29-11-30-21(20)27/h2-11,24H,1H3,(H,28,31)(H,32,33)(H2,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
HANMI PHARM. CO., LTD US Patent					Assay Description The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...				US Patent US9156852 (2015) BindingDB Entry DOI: 10.7270/Q24T6H4D
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