Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM200525'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM200525 (US9670231, 1.40) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-12(2-4-13)24(33)31-21-20-16-11-14(5-7-17(16)35-22(20)21)34-18-9-10-29-23-15(18)6-8-19(32)30-23/h1-5,7,9-11,20-22H,6,8H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
BeiGene, Ltd. US Patent					Assay Description TBD				US Patent US9670231 (2017) BindingDB Entry DOI: 10.7270/Q2F18WWF
					More data for this Ligand-Target Pair