Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM313632'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM313632 (N-(3-(2-(2- hydroxyethoxy)-6- (tetrahydro-2H-pyran...) Show SMILES Cc1ccc(NC(=O)c2cc(cnn2)C(F)(F)F)cc1-c1cc(OCCO)nc(c1)C1CCOCC1 Show InChI InChI=1S/C25H25F3N4O4/c1-15-2-3-19(30-24(34)22-12-18(14-29-32-22)25(26,27)28)13-20(15)17-10-21(16-4-7-35-8-5-16)31-23(11-17)36-9-6-33/h2-3,10-14,16,33H,4-9H2,1H3,(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...				US Patent US10167279 (2019) BindingDB Entry DOI: 10.7270/Q2W0981V
					More data for this Ligand-Target Pair