Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50095420 (5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-thioph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Research Center Curated by ChEMBL | Assay Description Inhibitory concentration against raf kinase. | Bioorg Med Chem Lett 11: 2775-8 (2001) BindingDB Entry DOI: 10.7270/Q2NS0VD5 | |||||||||||
More data for this Ligand-Target Pair |