Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rap guanine nucleotide exchange factor 4' and Ligand = 'BDBM50175143'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50175143 (CHEMBL3809313) Show SMILES Cc1cc(C)c(Nc2c(C)cc(C)cc2C)c(C)c1 Show InChI InChI=1S/C18H23N/c1-11-7-13(3)17(14(4)8-11)19-18-15(5)9-12(2)10-16(18)6/h7-10,19H,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of 8-NBD-cAMP binding to EPAC2 (unknown origin) by microplate reader analysis				ACS Med Chem Lett 7: 460-4 (2016) Article DOI: 10.1021/acsmedchemlett.5b00477 BindingDB Entry DOI: 10.7270/Q2NC6335
					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50175143 (CHEMBL3809313) Show SMILES Cc1cc(C)c(Nc2c(C)cc(C)cc2C)c(C)c1 Show InChI InChI=1S/C18H23N/c1-11-7-13(3)17(14(4)8-11)19-18-15(5)9-12(2)10-16(18)6/h7-10,19H,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of EPAC2 (unknown origin) assessed as reduction in cAMP-mediated guanine nucleotide exchange factor activity in presence of C-terminal tru...				ACS Med Chem Lett 7: 460-4 (2016) Article DOI: 10.1021/acsmedchemlett.5b00477 BindingDB Entry DOI: 10.7270/Q2NC6335
					More data for this Ligand-Target Pair