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Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-4' and Ligand = 'BDBM50182691'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor tyrosine-protein kinase erbB-4


(Homo sapiens (Human))		BDBM50182691
PNG
(CHEMBL383499 | N-[4-[(3-chloro-4-fluorophenyl)amin...)
Show SMILES CC(C)N(CC#CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cn1)C(C)C
Show InChI InChI=1S/C23H24ClFN6O/c1-14(2)31(15(3)4)9-5-6-22(32)30-21-11-17-20(12-26-21)27-13-28-23(17)29-16-7-8-19(25)18(24)10-16/h7-8,10-15H,9H2,1-4H3,(H,26,30,32)(H,27,28,29)
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Similars
Article
PubMed
n/an/a 538n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of erbB4 fusion protein expressed in baculovirus by ELISA

J Med Chem 49: 1475-85 (2006)


Article DOI: 10.1021/jm050936o
BindingDB Entry DOI: 10.7270/Q2ZS2X96
More data for this
Ligand-Target Pair