Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50263159'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 1 (Mus musculus)	BDBM50263159 (CHEMBL4065014) Show SMILES Cc1cc(Nc2nc(Nc3ccc(NC(=O)C4CC4)cc3)nc(n2)N2CCOCC2)n[nH]1 Show InChI InChI=1S/C21H25N9O2/c1-13-12-17(29-28-13)24-20-25-19(26-21(27-20)30-8-10-32-11-9-30)23-16-6-4-15(5-7-16)22-18(31)14-2-3-14/h4-7,12,14H,2-3,8-11H2,1H3,(H,22,31)(H3,23,24,25,26,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry , University of Antwerp , Universiteitsplein 1 , Wilrijk-Antwerp 2610 , Belgium. Curated by ChEMBL					Assay Description Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...				J Med Chem 61: 1895-1920 (2018) Article DOI: 10.1021/acs.jmedchem.7b01449 BindingDB Entry DOI: 10.7270/Q2930WNQ
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Mus musculus)	BDBM50263159 (CHEMBL4065014) Show SMILES Cc1cc(Nc2nc(Nc3ccc(NC(=O)C4CC4)cc3)nc(n2)N2CCOCC2)n[nH]1 Show InChI InChI=1S/C21H25N9O2/c1-13-12-17(29-28-13)24-20-25-19(26-21(27-20)30-8-10-32-11-9-30)23-16-6-4-15(5-7-16)22-18(31)14-2-3-14/h4-7,12,14H,2-3,8-11H2,1H3,(H,22,31)(H3,23,24,25,26,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry , University of Antwerp , Universiteitsplein 1 , Wilrijk-Antwerp 2610 , Belgium. Curated by ChEMBL					Assay Description Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...				J Med Chem 61: 1895-1920 (2018) Article DOI: 10.1021/acs.jmedchem.7b01449 BindingDB Entry DOI: 10.7270/Q2930WNQ
					More data for this Ligand-Target Pair