Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50300696'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50300696 (CHEMBL574349 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(OCCCN4CCOCC4)ccc32)no1 Show InChI InChI=1S/C30H34N6O4S/c1-30(2,3)26-18-27(34-40-26)33-28(37)31-21-7-5-20(6-8-21)23-19-36-24-10-9-22(17-25(24)41-29(36)32-23)39-14-4-11-35-12-15-38-16-13-35/h5-10,17-19H,4,11-16H2,1-3H3,(H2,31,33,34,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding affinity to FLT3 catalytic domain expressed in HEK293 cells by competitive binding assay				J Med Chem 52: 7808-16 (2009) Article DOI: 10.1021/jm9007533 BindingDB Entry DOI: 10.7270/Q2319VZ6
					More data for this Ligand-Target Pair