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Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3 [D835H]' and Ligand = 'BDBM319787'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3 [D835H]


(Homo sapiens (Human))		BDBM319787
PNG
(5,6-dibromo-4-nitro-2-(piperazin-1-yl)-1-(propan-2...)
Show SMILES CC(C)n1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1
Show InChI InChI=1S/C14H17Br2N5O2/c1-8(2)20-10-7-9(15)11(16)13(21(22)23)12(10)18-14(20)19-5-3-17-4-6-19/h7-8,17H,3-6H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 28n/an/an/an/an/a



SELVITA S.A.

US Patent


Assay Description
Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...

US Patent US10174013 (2019)


BindingDB Entry DOI: 10.7270/Q2QR5069
More data for this
Ligand-Target Pair