new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50075214'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50075214
PNG
(CHEMBL3414876)
Show SMILES Cc1ccc(cc1)S([O-])(=O)=O.ON1C(=O)Cc2cc(Cc3ccc(cc3)-c3cc[nH+]cc3)ccc2C1=O
Show InChI InChI=1S/C21H16N2O3/c24-20-13-18-12-15(3-6-19(18)21(25)23(20)26)11-14-1-4-16(5-2-14)17-7-9-22-10-8-17/h1-10,12,26H,11,13H2/p+1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 900n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of HIV1 recombinant reverse transcriptase polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by li...


J Med Chem 58: 651-64 (2015)


Article DOI: 10.1021/jm501132s
BindingDB Entry DOI: 10.7270/Q2W95BWG
More data for this
Ligand-Target Pair
Reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50075214
PNG
(CHEMBL3414876)
Show SMILES Cc1ccc(cc1)S([O-])(=O)=O.ON1C(=O)Cc2cc(Cc3ccc(cc3)-c3cc[nH+]cc3)ccc2C1=O
Show InChI InChI=1S/C21H16N2O3/c24-20-13-18-12-15(3-6-19(18)21(25)23(20)26)11-14-1-4-16(5-2-14)17-7-9-22-10-8-17/h1-10,12,26H,11,13H2/p+1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of Moloney murine leukemia virus reverse transcriptase polymerase activity using Td100/Pd18 DNA-DNA substrate incubated for 30 mins by flu...


J Med Chem 58: 651-64 (2015)


Article DOI: 10.1021/jm501132s
BindingDB Entry DOI: 10.7270/Q2W95BWG
More data for this
Ligand-Target Pair