Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2 [1-552]' and Ligand = 'BDBM598663'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 [1-552] (Homo sapiens (Human))	BDBM598663 (N-(2-(3,8-diazabicyclo[3.2.1]octan-8-yl)-6-(triflu...) Show SMILES FC(F)(F)c1cc(Nc2ccc3[nH]ncc3c2)nc(n1)N1C2CCC1CNC2 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K
					More data for this Ligand-Target Pair