Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribonucleoside-diphosphate reductase large subunit/subunit M2 (Homo sapiens (Human)) | BDBM50153688 ((S)-3-[(S)-2-((S)-2-{(S)-2-[(2S,3R)-2-((S)-2-Acety...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition of mammalian ribonucleotide reductase in a standard dTTP-dependent GDP reductase assay | Bioorg Med Chem Lett 14: 5301-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.028 BindingDB Entry DOI: 10.7270/Q25Q4VJF | |||||||||||
More data for this Ligand-Target Pair |